the plasma antioxidant activity of superoxide dismutase enzyme in osteoporosis
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abstract
osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. some studies show that osteoblasts can create inter-cellular free radicals that lead to cellular death. superoxide dismutase (sod) plays an essential role in cell defense against reactive oxygen metabolites. the purpose of this study was to measure the plasma sod activities in iranian women with osteoporosis compared to the control group. sod activity was measured spectrophotometrically at 540 nm in 192 women. plasma activity of sod (mean ± sd) was 1.72 ± 0.79 mg protein in the control group, 2.05 ± 0.87 mg protein in patients as a whole [(mild osteopenia + severe osteopenia and osteoporosis) (t-score
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Journal title:
acta medica iranicaجلد ۴۶، شماره ۶، صفحات ۴۴۱-۴۴۶
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